A case of influenza A H3N2 complicated with Kawasaki disease and liver function impairment

Background: Studies have found that multiple viral infections are related to the occurrence of Kawasaki disease. It has not been reported in the world which H3N2 influenza A and Kawasaki disease occurred simultaneously. Children with influenza virus infection and symptoms associated with Kawasaki disease should be highly alert. Case presentation: Here we present a 2 -year -old Chinese girl who was treated with oseltamivir and cefoperazone sulbactam for H3N2influenza infection and sepsis. The girl's body temperature remained high and liver enzymes increased significantly. The child was diagnosed with Kawasaki disease by a pediatric cardiologist and The patient recovered completely after being treated with gamma globulin. Conclusion: We hope that our case report will guide clinicians to be vigilant about Kawasaki disease when high fever persists in children with H3N2 influenza.