Prevalence and related risk factors of psychotic symptoms among inpatients infected with COVID-19 during the second wave pandemic

Abstract Background Possibility of psychotic symptoms and related risk factors among the normal person and infected patients during the outbreak of COVID-19 has been widely investigated in previous studies. With the arrival of the second wave of the epidemic in many countries around the word, the accordingly mental health outcomes were unclear yet, especially the mental health outcomes among infected patients. It aims to explore the prevalence of and related risk factors associated with psychotic symptoms in COVID-19 infected inpatients during the second wave. Method: A cross-sectional survey was conducted in five isolated wards of a designated hospital in Beijing, China, from 1 July to 15 July, 2020. The Mini-International Neuropsychiatric Interview (M.I.N.I) was conducted to assess the psychiatric disorders, and a serious of scales was used to measure self-reported psychotic symptoms and psychosomatic factors. Multivariate regression analysis was used to analyze the risk factors associated with psychotic symptoms. Results Among 199 infected participants, the prevalence of generalized anxiety symptoms is 51.3%, of depressive symptoms 41.2%, of PTSD symptoms 33.6%. Loneliness, hope, coping strategies, history of mental disorders were shared risk or protective factors across several psychotic symptoms. Perceived impact by COVID-19 is the specific risk factor associated with state anxiety symptoms. Conclusions The prevalence of symptoms of depression, anxiety and PTSS/PTSD is high among infected inpatients during the second wave of pandemic in Beijing. Clinical doctors must realize that infected inpatients during the second wave of pandemic are likely to suffer from depressive disorder, anxiety disorders and PTSS/PTSD, as well as some neuropsychiatric syndromes. Specific mental health care is urgently needed to help inpatients cope with the virus during the second wave of pandemic.