Sexual Dysfunction in Women with Inflammatory Bowel Disease

Daniel Mayrhofer, Jenny Shtokman-Shehab, Clemens Dejaco, Daniela Dörfler, Nadja Valenta-Taschler, Nora Rosenberg, Florian Heinzl, Johannes Ott, Klára Rosta
In: Journal of Clinical Medicine · 2025 · vol. 14(7) , pp. 2236 · doi:10.3390/jcm14072236 · PMID:40217687 · W4408827774
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This study found that female patients with inflammatory bowel disease reported significantly lower sexual function scores and used contraception less often than healthy controls.

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Abstract

Background: Crohn’s disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBDs) characterized by various clinical symptoms including abdominal pain, diarrhea, fatigue, and extraintestinal manifestations, which negatively affect a patient’s quality of life. Both mainly occur in adolescence and young adulthood and therefore affect women in their sexually active period. The aim of this study was to assess the effect of IBD on female sexuality and attitudes towards contraception. Methods: A prospective cross-sectional survey study was conducted at the Medical University of Vienna, Austria. Data were collected using a self-designed questionnaire, which included questions on demographics, gynecological patient history, contraceptive choices, and fertility, as well as the Female Sexual Functionality Index (FSFI). Results: A total of 83 female patients with IBD (CD: n = 47, UC: n = 36) and 340 healthy control participants between the ages of 18 and 50 years were investigated. Demographic parameters did not differ between the groups; however, mean FSFI scores were significantly lower in the patient group (p < 0.001). Significantly fewer patients in the IBD group used contraception (p = 0.008). No significant differences regarding conception rates and infertility rates were noted between patients with IBD and control participants (p = 0.533 and p = 0.506, respectively). Conclusions: Female sexuality is significantly impaired in patients with IBD. Women with IBD do not receive sufficient information regarding contraception and should be screened for sexual dysfunction to optimize their quality of life.

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last seen: 2026-06-10T17:14:06.276822+00:00
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