Synthesis and Characterization of Two Danazol Derivatives
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Two danazol derivatives were synthesized and characterized, with compound 6 showing higher lipophilicity and lower steric hindrance than compound 3.
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Abstract
Two danazol derivatives were synthesized and characterized by spectral analyses. In order to characterize the structural and chemical requirements of danazol derivatives, several parameters such as logP , π, R m and V m were evaluated. The results showed an increase in the values of logP for the compound 6 in comparison with 3. The compound 3 showed an increase in the values of π, R V m and V V m with respect to 6. These data indicate a high degree of lipophilicity and a low steric impediment for compound 6 in comparison with 3.
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References (3)
- W6602610289 via openalex
- W6837517575 via openalex
- doi:10.1007/s00706-010-0263-y via openalex
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- last seen: 2026-05-10T10:41:00.428268+00:00
License: CC0
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