Aminophenyl derivatives as selective androgen receptor modulators
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Abstract
Disclosed is an azabicyclo[3.2.1]oct-8-yl compound of formula (I) wherein R1 is cyano or nitro and wherein the rest of the substituents are disclosed within the specification. Also disclosed is the use of the compound of formula (I) in the manufacture of a medicament for the treatment of a condition such as hypogonadism, lower than normal testosterone plasma levels, infertility in males, erectile dysfunction in males, andropause in males, endometriosis in females, dyspareunia in females, vaginismus in females, sexual arousal disorders in females, sexual orgasmic disorders in females, disorders of libido in males, cachexia, HIV wasting, critical illnesses in which muscle wasting is apparent, sarcopenia, frailty, short stature, dwarfism, bone density loss, mood disorders, depression, impaired cognitive functions, neurodegenerative disorders, xerophthalmia, metabolic disorders, autoimmune disease, cardiovascular disorders, obesity, anemia, burns, prostate cancer, and schizophrenia.
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- last seen: 2026-07-28T06:14:09.330459+00:00