Combined Cataract and Retina Surgery for Granular Corneal Dystrophy with Rhegmatogenous Retinal Detachment：a case report

Combined Cataract and Retina Surgery for Granular Corneal Dystrophy with Rhegmatogenous Retinal Detachment：a case report | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Combined Cataract and Retina Surgery for Granular Corneal Dystrophy with Rhegmatogenous Retinal Detachment：a case report Zhencheng Ge, Yiqing Gong This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8757337/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background Granular corneal dystrophy with rhegmatogenous retinal detachment is relatively rare, and the granular opacities in the cornea can interfere with fundus examination and surgical treatment. This article presents the diagnosis and surgical management of a patient with granular corneal dystrophy combined with rhegmatogenous retinal detachment, and discusses the possible underlying pathogenesis. Case presentation: We describe the clinical course of a 51-year-old female patient with granular corneal dystrophy complicated by rhegmatogenous retinal detachment, who underwent combined cataract and retinal surgery with silicone oil tamponade. One year postoperatively, following silicone oil removal, her visual acuity remained stable at 0.1. Conclusion Although the co-occurrence of granular corneal dystrophy and rhegmatogenous retinal detachment is relatively rare in clinical practice, this case provides insights into retinal surgery under suboptimal corneal conditions. Moreover, it underscores the necessity of timely fundus examination for such patients. Corneal dystrophy Retinal detachment Full Text Additional Declarations No competing interests reported. Supplementary Files originalimageXiafangXu.zip Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-8757337","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":588142287,"identity":"d69c3990-a847-4f41-b718-6140217702e5","order_by":0,"name":"Zhencheng Ge","email":"","orcid":"","institution":"Department of Ophthalmology, Affiliated People's Hospital, Jiangsu University","correspondingAuthor":false,"prefix":"","firstName":"Zhencheng","middleName":"","lastName":"Ge","suffix":""},{"id":588142288,"identity":"b1ece158-7f98-4e4c-9eb3-67f7673c7d4b","order_by":1,"name":"Yiqing Gong","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA7klEQVRIiWNgGAWjYNACAwYeBgbmA0CWBQOISawWtgQGhgQJYrWAAY8BcVrk3XsPv+YpsJYx51/z8THvDwk5fp4DjB8+5uDWYnjmXJo1j0E6j+WMt5uNeRIkjCV7G5glZ27Do2VGjpkxj8FhHoMbZ7dJA7UkbjjPwMbMS5yWM8+I0yIvkWP8GKzlfA8bRMvZBvxaDHjOmDHOAfrF4AabseGcNKBfeg424/WLfHuP8Yc3f6ztDc4ffvjgjY0NMMSSD374iM+WAwxsUjwMzAwMEgkwMcYG3OpBtjQwMH/8AdLCfwCvwlEwCkbBKBjBAAAn8Uuv195SpgAAAABJRU5ErkJggg==","orcid":"","institution":"Zhenjiang Kangfu Eye Hospital","correspondingAuthor":true,"prefix":"","firstName":"Yiqing","middleName":"","lastName":"Gong","suffix":""}],"badges":[],"createdAt":"2026-02-01 15:38:32","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-8757337/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-8757337/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":107637252,"identity":"157ae4cb-e335-4e77-9512-7c2459269a75","added_by":"auto","created_at":"2026-04-23 12:41:42","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":384680,"visible":true,"origin":"","legend":"","description":"","filename":"CombinedCataractandRetinaSurgeryforGranularCornealDystrophywithRhegmatogenousRetinalDetachmentacasereport.pdf","url":"https://assets-eu.researchsquare.com/files/rs-8757337/v1_covered_37ab13df-529d-4168-a3e4-765b85ce9b07.pdf"},{"id":102329186,"identity":"382b7b73-3af0-4912-9b55-d8fda6cb0dd7","added_by":"auto","created_at":"2026-02-10 15:00:52","extension":"zip","order_by":0,"title":"","display":"","copyAsset":false,"role":"supplement","size":20377467,"visible":true,"origin":"","legend":"","description":"","filename":"originalimageXiafangXu.zip","url":"https://assets-eu.researchsquare.com/files/rs-8757337/v1/98931e8697b886be7941854e.zip"}],"financialInterests":"No competing interests reported.","formattedTitle":"Combined Cataract and Retina Surgery for Granular Corneal Dystrophy with Rhegmatogenous Retinal Detachment：a case report","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Corneal dystrophy, Retinal detachment","lastPublishedDoi":"10.21203/rs.3.rs-8757337/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-8757337/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003ch2\u003eBackground\u003c/h2\u003e \u003cp\u003eGranular corneal dystrophy with rhegmatogenous retinal detachment is relatively rare, and the granular opacities in the cornea can interfere with fundus examination and surgical treatment. This article presents the diagnosis and surgical management of a patient with granular corneal dystrophy combined with rhegmatogenous retinal detachment, and discusses the possible underlying pathogenesis.\u003c/p\u003e\u003ch2\u003eCase presentation:\u003c/h2\u003e \u003cp\u003eWe describe the clinical course of a 51-year-old female patient with granular corneal dystrophy complicated by rhegmatogenous retinal detachment, who underwent combined cataract and retinal surgery with silicone oil tamponade. One year postoperatively, following silicone oil removal, her visual acuity remained stable at 0.1.\u003c/p\u003e\u003ch2\u003eConclusion\u003c/h2\u003e \u003cp\u003eAlthough the co-occurrence of granular corneal dystrophy and rhegmatogenous retinal detachment is relatively rare in clinical practice, this case provides insights into retinal surgery under suboptimal corneal conditions. 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