Clinical Observation of Chinese Herbal Medicine of Clearing Heat and Expelling Toxicity, Activating Blood and Removing Stasis for Treatment of Stage III to IV Endometriosis Infertility After Laparoscopic Operation

Objective To observe the clinical effects of therapy of clearing heat and expelling toxicity,activating blood and removing stasis for the treatment of stage Ⅲ to Ⅳ endometriosis infertility after laparoscopic operation.Methods The qualified 80 patients with stage Ⅲ to Ⅳ endometriosis infertility after laparoscopic operation were randomized into treatment group and control group.The treatment group(N =50) was given Chinese herbal medicine with the actions of clearing heat and expelling toxicity,activating blood and removing stasis,and the control group(N=30) was given gonadotrophin-releasing hormone(GnRH).Clinical outcomes of pregnancy rate,dysmenorrhea recurrence,and recurrence of endometrial cyst of ovary were observed in both groups.After treatment,the effects on relieving dysmenorrhea and traditional Chinese medical syndromes were also compared in both groups.Results After treatment,the treatment group had higher pregnancy rate than the control group,the difference being significant(P0.05).The results of one-year observation showed that the recurrence rate of dysmenorrhea was lower in the treatment group than that in the control group(P 0.05).There was no significant difference in the recurrence rate of endometrial cyst of ovary one year after laparoscopic operation(P 0.05).After treatment,the scores of traditional Chinese medical syndromes and dysmenorrhea were both evidently improved in both groups(P 0.01 compared with those before treatment),and the improvement in the treatment group was superior to that in the control group(P0.05 or P0.01).Conclusion For the patients with stage Ⅲ to Ⅳ endometriosis infertility after laparoscopic operation,the application of Chinese herbal medicine with the actions of clearing heat and expelling toxicity,activating blood and removing stasis shows satisfactory effect on increasing pregnancy rate,reducing the recurrence of endometrial cyst of ovary and relieving dysmenorrhea.