CYCLOALKYL INHIBITORS OF PROTEIN FARNESYLTRANSFERASE

DOHERTY ANNETTE MARIAN, KALTENBRONN James Stanley, LEONARD DANIELE M, MC NAMARA Dennis Joseph
1999
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The paper describes novel cycloalkyl inhibitors of protein farnesyltransferase and their preparation methods for controlling tissue proliferative diseases including endometriosis.

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Abstract

Novel inhibitors of protein farnesyltransferase enzymes are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer, restenosis, atherosclerosis, psoriasis, and endometriosis.

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europepmc
last seen: 2026-07-29T06:27:48.050232+00:00