Gamete intrafallopian transfer (GIFT): an alternate method of conception in couples with unexplained infertility, endometriosis and oligo-asthenospermia.

P C Wong, Wong Pc, C L Chan, Chan Cl, M P Hamilton, Hamilton Mp, Ng Sc, S C Ng, A Bongso, Ariff Bongso, Wong Yc, Y C Wong, C Anadakumar, V Goh, Goh, Ratnam Ss, S S Ratnam
Annals of the Academy of Medicine, Singapore · 1988 · vol. 17(2) , pp. 247–50 · PMID:3044262 · W2413369243
article OA: closed CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

Gamete intrafallopian transfer (GIFT) cycles in couples with unexplained infertility, endometriosis, or male factor resulted in a 24.6% pregnancy rate, with four oocytes optimal for transfer and male factor patients faring the worst.

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Abstract

138 treatment cycles of GIFT were carried out in couples with mainly unexplained infertility, endometriosis and male factor. The overall pregnancy rate was 24.6%, abortion 29.2%, multiple pregnancy 20.6% and ectopic pregnancy 0%. Four oocytes seem to be the optimal number of oocytes to be transferred. Patients with male factor infertility fared the worse in comparison with the other groups. Successful in-vitro fertilization of excess eggs did not correlate with a positive outcome of the GIFT procedure.

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Condition tags

endometriosisinfertility

MeSH descriptors

Fallopian Tubes Infertility, Female Infertility, Male Oocytes Reproductive Techniques Spermatozoa Endometriosis Endometriosis Female Humans Infertility, Female Infertility, Male Male Oligospermia Oligospermia Oocytes Ovarian Follicle Ovarian Follicle Pregnancy Spermatozoa

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europepmc
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License: CC0 · commercial use OK