Clinical Manifestations of Perinatal Pregnant Women with Pulmonary Embolism

Purpose: ： To analyze the clinical manifestations of perinatal pregnant women with pulmonary embolism(PE) and improve the understanding of maternal PE disease. Methods: ： We retrospectively reviewed maternities diagnosed with PE in a maternity and infant hospital between July 2018 and June 2020. Patients were divided into different groups according to risk stratification. Clinical data were collected and statistically analyzed by SPSS. Results: : A total of 49 patients, with an average age of (32.31±4.17) years at delivery were clarified into low-risk group (28 patients, 57.1%) and medium-risk group (21 patients, 42.9%). The medium-risk group had a significant higher serum level of TnI (0.0052±0.0073 ng/ml) compared with low-risk group (0.0009±0.0013 ng/ml). Although d-dimer level (5.1±3.6 mg/l) of selected patients were higher than normal range at the time of admitting, a significant increasing trend was still observed when diagnosed with PE ( p =0.012 in low-risk group, p= 0.005 in medium-risk group). The location of thrombosis distributed mainly in right lung (28(57.1%)) and lower field of lung (32(65.3%)) according to CTA image, while 5 cases of right ventricular enlargement were limited in medium-risk group. While 87.8% of patients were asymptomatic. The frequencies of PE in Febraury 2020 and March 2020 were higher compared to any other month, which was in accordance with the first episode period of COVID-19 in China. Conclusion: Perinatal PE is frequently found in elderly pregnant women, with a more benign clinical presentation compared with reported data. Dynamic monitoring of d-dimer may have more clinical value for early identification of perinatal PE.