[Effects of Nd(2)O(3) exposure of rare earth particles on C57 BL/6J male mice sex hormone secretion and CYP11A1/PLZF/STRA8 protein expression].

Huanhuan Song, Ning Bu, Yanrong Gao, Y H Zhao, Zhao Yongtao, X M Shi, Siqi Wang
In: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases · 2022 · vol. 40(12) , pp. 881–887 · doi:10.3760/cma.j.cn121094-20210817-00401 · PMID:36646477 · W4316928105
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Abstract

The rare earth particulate Nd(2)O(3) may interfere with the expression of CYP11A1, PLZF and STRA8 protein, thereby causing the disorder of sex hormone secretion in the body, the maintenance of spermatogonia and the obstruction of the process of meiosis, causing reproductive function damage.

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