Pharmacodynamic study of Kaiyuan granules in experimental rat endometriosis
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CC0
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Kaiyuan granules significantly reduced ectopic endometrial implant volumes and induced epithelial atrophy in a rat model of experimental endometriosis.
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Abstract
Objective To evaluate the inhibiting effect of Kaiyuan granules on ectopic endometrial implants in rats. Methods Endometriosis models in rats were developed by surgical operations.Rats were sacrificed;volumes and pathological changes of endometrial transplant were observed after 2 weeks of treatments with Kaiyuan granules.Results Transplant volumes were significantly reduced in the moderate-dose and high-dose Kaiyuan granules group.Histologic examination of the explants showed an atrophy of epithelium and a decrease of endometrial glands.Conclusions The growth of ectopic endometrium can be inhibited with a moderate or high dose Kaiyuan granules.
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- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0
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