Male Breast Cancer with Ureteral Metastasis: a case report

Abstract Background: Breast cancer is rare in men and there is no report of male breast cancer (MBC) with ureteral metastasis. In this study, we report a special case of MBC with ureteral metastasis. Case presentation: A 60-year-old man was diagnosed with breast cancer and lymph nodes metastasis. After surgery, chemotherapy and radiotherapy he was diagnosed with left arm metastasis. Then he received mass dissection and chemotherapy again. He was diagnosed with ureter metastasis because of hematuria. This patient took a Precitype gene test (immune index and PAM50) after several lines of treatment and the result indicated that this was a Luminal A subtype case, which was quite different from his immunohistochemical subtype. We adjusted his therapeutic regimen according to the genetic test but there was no obvious efficacy and he passed away five months later. Conclusions: MBC patients with urinary symptoms should be considered for the possibility of metastasis although urinary metastasis in breast cancer is rare. We still need more research and evidence of treatment recommendations for MBC.