[Clinical experiences in the treatment of endometriosis with the LH-RH analog buserelin with special reference to the post-therapy course].

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AI-generated summary by claude@2026-06, 2026-06-07

Buserelin therapy for endometriosis achieved ovarian downregulation and pain relief, but endometriosis symptoms recurred in most patients within 12 weeks after treatment.

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Abstract

The current therapy study with 50 patients showed that a reversible down regulation of the ovaries is possible. Particularly in cases with severe endometriosis a rapid release of pain can usually be achieved. Further development of the disease could be prevented and in two third of the cases even a partial reduction of tumor size. Within 12 weeks after the therapy the cycle is normally stabilized. But in about 70% of the patients the typical complaints of endometriosis were recurrent. The advantage of this treatment is the high acceptance of the patients in comparison to steroid medication. In long term administration it is mandatory to control bone and lipid metabolism.

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Condition tags

dysmenorrheaendometriosis

MeSH descriptors

Buserelin Endometriosis Genital Neoplasms, Female Adult Buserelin Dysmenorrhea Dysmenorrhea Endometriosis Endometriosis Female Follow-Up Studies Genitalia, Female Genitalia, Female Genital Neoplasms, Female Genital Neoplasms, Female Humans Luteinizing Hormone Luteinizing Hormone Progesterone Progesterone

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Source provenance

europepmc
last seen: 2026-06-11T06:19:48.454388+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:09:20.810540+00:00
License: CC0 · commercial use OK