Design and Analysis of a Biosensor Based on Surface Plasmon Resonance in a Photonic Crystal Fiber

Design and Analysis of a Biosensor Based on Surface Plasmon Resonance in a Photonic Crystal Fiber | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Design and Analysis of a Biosensor Based on Surface Plasmon Resonance in a Photonic Crystal Fiber A. Abdikian This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7085603/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 23 Sep, 2025 Read the published version in Plasmonics → Version 1 posted 10 You are reading this latest preprint version Abstract This study introduces the design and analysis of two surface plasmon resonance (SPR) biosensors based on photonic crystal fibers (PCFs) coated with a gold layer, utilizing the finite element method (FEM) in COMSOL Multiphysics. The investigation focuses on two structural configurations: circular and elliptical air holes in the first cladding ring. The \(\:y\) -polarized mode, due to stronger coupling with the surface plasmon polariton (SPP) mode, provided enhanced sensitivity. Phase matching occurred at ~ 0.67µm for an analyte refractive index of 1.37. The elliptical design showed higher confinement loss (131.8dB/cm) compared to the circular one (120.4dB/cm). As the analyte refractive index increased from 1.33 to 1.37, both confinement loss and wavelength sensitivity increased, with a red shift in resonance wavelength. Polynomial fitting showed strong linearity between resonance wavelength and analyte index, with adjusted \(\:{R}^{2}\) values of 0.9923 and 0.9927 for circular and elliptical designs, respectively. Final sensor resolutions were 3.22 × 10⁻⁶RIU and 3.15 × 10⁻⁶RIU. These results highlight the critical role of hole geometry in optimizing SPR-PCF biosensor performance. Surface plasmon polariton biosensor asymmetric configuration thin layer effective refractive index Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 23 Sep, 2025 Read the published version in Plasmonics → Version 1 posted Editorial decision: Revision requested 18 Aug, 2025 Reviews received at journal 15 Aug, 2025 Reviews received at journal 10 Aug, 2025 Reviewers agreed at journal 08 Aug, 2025 Reviewers agreed at journal 07 Aug, 2025 Reviewers agreed at journal 31 Jul, 2025 Reviewers invited by journal 21 Jul, 2025 Editor assigned by journal 10 Jul, 2025 Submission checks completed at journal 10 Jul, 2025 First submitted to journal 09 Jul, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7085603","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":488752359,"identity":"ccd863d3-ca87-4923-920a-e640e5dd984f","order_by":0,"name":"A. 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The investigation focuses on two structural configurations: circular and elliptical air holes in the first cladding ring. The \u003cspan class=\"InlineEquation\"\u003e\u003cspan class=\"mathinline\"\u003e\\(\\:y\\)\u003c/span\u003e\u003c/span\u003e-polarized mode, due to stronger coupling with the surface plasmon polariton (SPP) mode, provided enhanced sensitivity. Phase matching occurred at ~\u0026thinsp;0.67\u0026micro;m for an analyte refractive index of 1.37. The elliptical design showed higher confinement loss (131.8dB/cm) compared to the circular one (120.4dB/cm). As the analyte refractive index increased from 1.33 to 1.37, both confinement loss and wavelength sensitivity increased, with a red shift in resonance wavelength. Polynomial fitting showed strong linearity between resonance wavelength and analyte index, with adjusted \u003cspan class=\"InlineEquation\"\u003e\u003cspan class=\"mathinline\"\u003e\\(\\:{R}^{2}\\)\u003c/span\u003e\u003c/span\u003e values of 0.9923 and 0.9927 for circular and elliptical designs, respectively. Final sensor resolutions were 3.22 \u0026times; 10⁻⁶RIU and 3.15 \u0026times; 10⁻⁶RIU. 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