Immunity And Endometriosis: A Short Review

Endometriosis is a prevalent disorder of the female reproductive system that frequently demonstrates malignant-like characteristics, including invasive growth and recurrence. Despite extensive investigation, the precise mechanisms underlying its pathogenesis remain incompletely elucidated. Accumulating evidence indicates that dysregulation of the immune system plays a central role in disease development and progression. Alterations in both the number and function of immune cell populations, such as macrophages, T and B lymphocytes, and natural killer (NK) cells, have been consistently documented. These findings have led to the hypothesis that immunotherapy may represent a promising novel strategy for the treatment of endometriosis. Keywords : Endometriosis; macrophages; immunity; NK cells; autoimmunity