凋亡与子宫内膜异位症研究进展

于春明, 邱晓红, 路莉, 王德莹, 陈秀慧
In: Chin J Postgrad Med · 2014 · vol. 37(36) , pp. 56–58 · doi:10.3760/cma.j.issn.1673-4904.2014.36.021 · W3032371873
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Abstract

子宫内膜异位症(endometriosis,EMs)是一种常见的妇科良性疾病,在育龄妇女中的发病率为6％ ～ 10％,20％ ～ 50％不孕患者患有EMs[1].EMs发病机制尚不明确,研究发现凋亡在EMs的发生、发展中具有重要作用.EMs患者子宫内膜细胞凋亡减少伴随着凋亡抑制因子增加和凋亡促进因子减少.提示内膜细胞对凋亡的易感性降低.提高其在异常部位的生长能力,最终导致EMs的发生[2].现综述凋亡与EMs发病及治疗的研究现状。

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endometriosis

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