Clinical effect of the LNG-IUS in treating 75 cases of adenomyosis.

Objective To investigate clinical therapeutic effect of Mirena(levonorgestrel-intrauterine system,LNG-IUS) treatment for patients with Adenomyosis.Methods Enrolled patients with adenomyosis(n=75) .Dysmenorrhea grading(visual analogue system-VAS) ,pictorial blood loss assessment chart(PBAC) for menorrhagia,uterine volume and carbohydrate antigen 125(CA125) ,etc.were collected from Pre-treatment,3,6,12,24 and 36th months after treatment.Results One year and two-year after insertion mirena,VAS,PBAC,uterine volumes and CA125 were significant lower than pre-insertion,uterine volumes and CA125 at three-year after insertion compared with pre-insertion had no significant difference.Conclusion LNG-IUS was an effective and safe treatment for patients with adenomyosis.LNG-IUS therapeutic potency was likely to decrease after 24 months of its placements.