Abstract
This study aimed to evaluate the predictive value of preoperative ultrasonographic assessment and serum CA-125 levels in estimating intraoperative endometriosis staging and adhesion scores in women diagnosed with endometriosis.Preoperative ultrasonographic evaluation and serum CA-125 measurements were performed in 152 women aged 21–45 years who presented to the gynecology and infertility outpatient clinic with complaints of pelvic pain, dysmenorrhea, or dyspareunia and were clinically suspected of having endometriosis. All patients underwent intraoperative staging of endometriosis. In appropriate cases, intraoperative tubal patency was assessed using methylene blue dye. The relationship between preoperative findings and intraoperative parameters was statistically analyzed.The mean age of the participants was 29.9 ± 6.91 years, and the mean serum CA-125 level was 59.92 ± 6.30 U/mL. A statistically significant correlation was found between preoperative CA-125 plasma concentration and both endometriosis stage and adhesion score. Similarly, a significant correlation was observed between the size of ultrasonographically detected lesions and both endometriosis stage and adhesion score. No significant association was found between tubal patency and preoperative CA-125 levels, ultrasonographic findings, or endometriosis stage. Demographic variables such as age, marital status, and number of pregnancies showed no significant correlation with endometriosis stage, adhesion severity, or serum CA-125 levels.Preoperative ultrasonographic evaluation and serum CA-125 levels are important predictive markers in patients with endometriosis. These parameters may guide surgical decision-making and operative planning, particularly in determining the surgical approach and the need for preoperative preparation. Special attention should be given to disease stage, lesion size, and adhesion score when planning surgical intervention.
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PREDICTIVE VALUE OF PREOPERATIVE ULTRASONOGRAPHY AND SERUM CA-125 LEVELS FOR ENDOMETRIOSIS STAGE AND ADHESION SCORE
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Description
This study aimed to evaluate the predictive value of preoperative ultrasonographic assessment and serum CA-125 levels in estimating intraoperative endometriosis staging and adhesion scores in women diagnosed with endometriosis.Preoperative ultrasonographic evaluation and serum CA-125 measurements were performed in 152 women aged 21–45 years who presented to the gynecology and infertility outpatient clinic with complaints of pelvic pain, dysmenorrhea, or dyspareunia and were clinically suspected of having endometriosis. All patients underwent intraoperative staging of endometriosis. In appropriate cases, intraoperative tubal patency was assessed using methylene blue dye. The relationship between preoperative findings and intraoperative parameters was statistically analyzed.The mean age of the participants was 29.9 ± 6.91 years, and the mean serum CA-125 level was 59.92 ± 6.30 U/mL. A statistically significant correlation was found between preoperative CA-125 plasma concentration and both endometriosis stage and adhesion score. Similarly, a significant correlation was observed between the size of ultrasonographically detected lesions and both endometriosis stage and adhesion score. No significant association was found between tubal patency and preoperative CA-125 levels, ultrasonographic findings, or endometriosis stage. Demographic variables such as age, marital status, and number of pregnancies showed no significant correlation with endometriosis stage, adhesion severity, or serum CA-125 levels.Preoperative ultrasonographic evaluation and serum CA-125 levels are important predictive markers in patients with endometriosis. These parameters may guide surgical decision-making and operative planning, particularly in determining the surgical approach and the need for preoperative preparation. Special attention should be given to disease stage, lesion size, and adhesion score when planning surgical intervention.
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