POSTMENOPOZAL HASTADA ENDOMETRİUMUN KEMİK METAPLAZİSİ: NADİR BİR OLGU

Aim: Osseous metaplasia of the endometrium is a rare benign condition that causes secondary infertility in women between 20 and 40 years of age, with a recent history of abortion. It is extremely rare in postmenopausal period. Here, we report a 55 years' old postmenopausal woman presented with vaginal bleeding, with a history of four previous curettages. It is important to exclude malignancy, clinically and pathologically, in differential diagnosis. Case report: A 55 years' old, five years' menopausal woman was admitted with vaginal bleeding symptom. Hyperechoic acoustic shadows were observed in the endometrial cavity in ultrasonography. There were bone tissue in the endometrial stroma in the histopathological evaluation of the probe curetting. Serum calcitonin, PTH, Vit D3, calcium, ionized calcium and phosphorus levels were in normal ranges. MR, following curetting, revealed residual bony particles within the endometrial cavity. Macroscopic and microscopic examination of the histerectomy material revealed bone in endometrial cavity. Discussion: There are different theories for the pathogenesis of osseous metaplasia of the endometrium. Today, the differentiation of endometrial stromal cells to osteoblasts is the most accepted one. It is generally recognised by ultrasonography. Probe curettage is the least invasive procedure for the diagnosis and treatment. Spontaneous pregnancy is generally obtained with the removal of bone fragments from the cavity. The remarkable features of our case are, the rarity of endometrial pathology, the postmenopausal status of our patient that is the second in the literature, vaginal bleeding symptom and history of four curettages, which the last one is 20 years ago.