Impact of PostCovid-19 on Perinatal Outcomes

Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) infection during pregnancy was associated with a number of adverse pregnancy outcomes, including miscarriage, preeclampsia, preterm birth, and stillbirth. The virus persistence can last for a long time, and the consequences of a previous coronavirus infection are currently under study. This study aimed to establish the clinical features of the course of pregnancy and childbirth in women with a history of asymptomatic coronavirus disease 2019 (COVID-19). This study was conducted in the Regional Perinatal Center N3 of Turkestan city, Kazakhstan from August to September 2021. A total of 229 participants were enrolled comprising individuals with (n=133, exposed group) or without a history of COVID-19 (n=96, unexposed group). There is a statistically significant strong relationship between a history of COVID-19 and the development of oligohydramnios (φ=0.743, p<0.001); medium strength between a history of COVID-19 and the presence of anemia, abnormal development of the placenta, cord entanglement, low birth weight and stillbirth (p<0.001). The past COVID-19 infection in pregnant women have long-term consequences in the form of placenta abnormal development and oligohydramnios, and as a result, the development of adverse perinatal outcomes.