Endometrioma mimicking ovarian cancer with unusual high levels of serum CA 125 and Ca 19-9

Nuri Peker, Ahmet Demir, Özgür Bige
2013 · vol. 2(4) , pp. 170–173 · doi:10.12808/bcs.v2i4.1033000043 · W1769187493
article OA: green CC0
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-15 ⓘ

This case describes a 35-year-old woman with a left ovarian endometrioma that mimicked ovarian cancer due to its size, free fluid, and elevated CA 125 and CA 19-9 levels.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-07, 2026-07-15 · read from full text ⓘ

This paper reports a case of a 35-year-old nulliparous woman referred for a 6×7 cm left ovarian mass with free fluid in the pouch of Douglas and markedly elevated serum CA 125 (1061 IU/mL) and CA 19-9 (896 IU/mL). Laparotomy was performed under suspicion of ovarian cancer, and an endometrioma adherent to the sigmoid colon was identified and excised; histopathology confirmed the diagnosis. The authors note that endometrioma presenting with ascites and high CA 125 and CA 19-9 levels that mimic ovarian cancer is rare. This paper is centrally about endometriosis — it describes an endometrioma that mimicked ovarian cancer with unusually high serum CA 125 and CA 19-9.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

AbstractA 35 year-old nulliparous woman was referred to our clinic with left ovarian mass (6x7 cm in size) accompanied by excessive free fluid at pouch of Douglas and elevated levels of serum CA 125 and CA 19-9 as 1061 IU/mL and 896 IU/mL, respectively. Laparotomy was performed with the suspect of ovarian cancer. Left ovarian endometrioma adherent to the sigmoid colon was observed and enuclated. Histopathological examination confirmed the diagnosis of endometrioma. Adnexal mass with free peritoneal fluid and high levels of tumor antigens; CA 125 and CA 19-9 mimicking ovarian cancer has been rarely diagnosed as endometrioma.Keywords: CA 125, CA 19-9, endometriosisÖzetOtuz beş yaşında, nullipar bir kadın adneksial kitle nedeni ile kliniğimize sevk edildi. Douglas boşluğunda belirgin sıvı birikimi ve yüksek CA 125 (1061 IU/mL) ve CA 19-9 (896 IU/mL) seviyeleri ile birlikte 6x7 cm boyutlarında sol over kitlesi vardı. Over kanseri ön tanısı ile laparotomi yapıldı. Sol yumurtalıkta sigmoid kolona yapışık endometrioma bulundu ve çıkartıldı. Histopatolojik inceleme endometrioma tanısını doğruladı. Asit ve yüksek CA 125 ve CA 19-9 düzeyleri ile birlikte olan yumurtalık kanserini taklit eden endometrioma nadir saptanan bir durumdur.Anahtar sözcükler: CA 125, CA 19-9, endometrioma
Full text 3,035 characters · extracted from oa-html · 2 sections · click to expand

Abstract

A 35 year-old nulliparous woman was referred to our clinic with left ovarian mass (6x7 cm in size) accompanied by excessive free fluid at pouch of Douglas and elevated levels of serum CA 125 and CA 19-9 as 1061 IU/mL and 896 IU/mL, respectively. Laparotomy was performed with the suspect of ovarian cancer. Left ovarian endometrioma adherent to the sigmoid colon was observed and enuclated. Histopathological examination confirmed the diagnosis of endometrioma. Adnexal mass with free peritoneal fluid and high levels of tumor antigens; CA 125 and CA 19-9 mimicking ovarian cancer has been rarely diagnosed as endometrioma.

Keywords

CA 125, CA 19-9, endometriosis Özet Otuz beş yaşında, nullipar bir kadın adneksial kitle nedeni ile kliniğimize sevk edildi. Douglas boşluğunda belirgin sıvı birikimi ve yüksek CA 125 (1061 IU/mL) ve CA 19-9 (896 IU/mL) seviyeleri ile birlikte 6x7 cm boyutlarında sol over kitlesi vardı. Over kanseri ön tanısı ile laparotomi yapıldı. Sol yumurtalıkta sigmoid kolona yapışık endometrioma bulundu ve çıkartıldı. Histopatolojik inceleme endometrioma tanısını doğruladı. Asit ve yüksek CA 125 ve CA 19-9 düzeyleri ile birlikte olan yumurtalık kanserini taklit eden endometrioma nadir saptanan bir durumdur. Anahtar sözcükler: CA 125, CA 19-9, endometrioma Anahtar Kelimeler Kaynakça - References - Yilmazer M, Sonmezer M, Gungor M. Unusually elevated serum carbohydrate antigen 125 (CA125) and CA19-9 levels as a result of unruptured bilateral endometrioma. Aust N Z J Obstet Gynaecol. 2003 Aug;43(4):329-30. - Kurata H, Sasaki M, Kase H, Yamamoto Y, Aoki Y, Tanaka K. Elevated serum CA125 and CA19-9 due to the spontaneous rupture of ovarian endometrioma. Eur J Obstet Gynecol Reprod Biol. 2002 Oct 10;105(1):75-6. - Harada T, Kubota T, Aso T. Usefulness of CA19-9 versus CA125 for the diagnosis of endometriosis.Fertil Steril. 2002 Oct;78(4):733-9. - Mabrouk M, Elmakky A, Caramelli E, Farina A, Mignemi G, Venturoli S, Villa G,Guerrini M, Manuzzi L, Montanari G, De Sanctis P, Valvassori L, Zucchini C, Seracchioli R. Performance of peripheral (serum and molecular) blood markers for diagnosis of endometriosis. Arch Gynecol Obstet. 2012 May;285(5):1307-12. - Kurdoglu Z, Gursoy R, Kurdoglu M, Erdem M, Erdem O, Erdem A. Comparison of the clinical value of CA 19-9 versus CA 125 for the diagnosis ofendometriosis. Fertil Steril. 2009 Nov;92(5):1761-3. doi: 10.1016/j.fertnstert.2009.05.022. Epub 2009 Jul 23. - Johansson J, Santala M, Kauppila A. Explosive rise of serum CA 125 following the rupture of ovarian endometrioma. Hum Reprod. 1998 Dec;13(12):3503-4. - Takemori M, Sugimura K. Ovarian chocolate cyst with markedly elevated serum CA19-9 level: a case report. Eur J Obstet Gynecol Reprod Biol. 1991 Dec 13;42(3):241-4. Ayrıntılar Birincil Dil İngilizce Konular - Bölüm - Yayımlanma Tarihi 26 Mart 2014 Gönderilme Tarihi 26 Mart 2014 Kabul Tarihi - Yayımlandığı Sayı Yıl 2013 Cilt: 2 Sayı: 4

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-html ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometrioma

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK