Leiomyoma cellulare in the broad ligament of the uterus--case report and review of literature.

In: Ginekologia polska · 2012 · vol. 83(4) , pp. 301–4 · PMID:22712264 · W169884178
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This report details a rare case of a 6-cm cellular leiomyoma removed laparoscopically from the broad ligament of a 29-year-old patient.

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This paper reports a single 29-year-old patient with a diagnosed lesion in the broad ligament of the uterus, evaluated as possibly a myoma of the female genital tract, and describes laparoscopic myomectomy by enucleation of a 6-cm interlamellar parametrial-type cellular lesion after preparation of the right parametrium tissue. Tumor markers were CA-125 of 10.14 U/ml, β-hCG 0.1 mIU/ml, and CRP 0.09 mg/l, and the patient was discharged on postoperative day 2 in good condition. Histopathology showed leiomyoma cellulare oedematosum, and the authors emphasize that cellular leiomyoma (<5%) in this broad-ligament location is extremely rare and their report is the first case described. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

UNLABELLED: Myomas are most often benign tumours of the female genital tract. Uterine fibroids are the most common myomas, while uterine cervix and intraligamentary ones are statistically less frequent. The most common histopathological form is the leiomyoma and the least common is the cellular leiomyoma (< 5%). OBJECTIVES: As emphasized in the introduction, interlamellar parametrial cellular leiomyomas are extremely rare. Leiomyoma cellulare in the broad ligament of the uterus is the first case of that, therefore, the following situation deserves a short analysis and publication. MATERIAL AND METHODS: A 29-year-old patient was admitted to the Obstetrics and Gynaecology Clinic in Poznań due to a diagnosed lesion in the broad ligament of the uterus, possibly a myoma of the female genital tract. Cancer Antigen (CA) 125 level was 10.14 U/ml, beta sub-unit of human chorionic gonadotropin (beta- HOG) was 0.1 mIU/ml, acute-phase protein was (CRP) 0.09 mg/l. The technique of laparoscopic myomectomy by enucleation of a 6-cm in diameter myoma was used after preparation of the right parametrium tissue. The patient left the hospital on the second postoperative day in good overall condition. RESULTS: Histopathology revealed leiomyoma cellulare oedematosum. CONCLUSIONS: The above description of CL in the broad ligament of the uterus is a highly unique case and thus, deserves some attention, a short analysis.
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Abstract

Myomas are most often benign tumours of the female genital tract. Uterine fibroids are the most common myomas, while uterine cervix and intraligamentary ones are statistically less frequent. The most common histopathological form is the leiomyoma and the least common is the cellular leiomyoma (<5%). Objectives: As emphasized in the introduction, interlamellar parametrial cellular leiomyomas are extremely rare. Leiomyoma cellulare in the broad ligament of the uterus is the first case of that, therefore, the following situation deserves a short analysis and publication. Material and methods: A 29-year-old patient was admitted to the Obstetrics and Gynaecology Clinic in Poznań due to a diagnosed lesion in the broad ligament of the uterus, possibly a myoma of the female genital tract. Cancer Antigen (CA) 125 level was 10.14 U/ml, beta sub-unit of human chorionic gonadotropin (β- HCG) was 0.1 mIU/ml, acute-phase protein was (CRP) 0.09 mg/l. The technique of laparoscopic myomectomy by enucleation of a 6-cm in diameter myoma was used after preparation of the right parametrium tissue. The patient left the hospital on the second postoperative day in good overall condition. Results: Histopathology revealed leiomyoma cellulare oedematosum. Conclusions: The above description of CL in the broad ligament of the uterus is a highly unique case and thus, deserves some attention, a short analysis.

Keywords

myomasfibroidsparametriumleiomyoma cellularethe broad ligament

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