Value-Based Evidence Accumulation as a Transdiagnostic Marker of General Distress

Abstract General distress cuts across psychiatric symptom domains, yet its computational correlates remain poorly defined. We examined whether drift rate—a core parameter indexing the efficiency of evidence accumulation—is more strongly associated with general distress than with domain-specific symptoms. In a cross-sectional online sample of 441 adults from the general population, participants completed a perceptual and value-based decision-making task, symptom assessments, and cognitive testing. Drift rates were estimated using hierarchical drift-diffusion modeling. Individuals with severe symptom elevations showed robust reductions in drift rate, particularly for value-based decisions. Mixed-effects models demonstrated that general distress, indexed by the Positive Symptom Distress Index, was more strongly associated with value-based than perceptual drift rate, even after accounting for all symptom domains. Value-based drift rate also explained variance in general distress beyond that accounted for by elevated symptoms across domains and selectively attenuated associations with somatization and paranoid symptoms. These findings suggest that value-based evidence accumulation captures a transdiagnostic component of distress-related impairment that is not reducible to symptom burden alone. Competing Interest Statement The authors have declared no competing interest.