Determine the IgG and IgM antibodies created against T. gondii infections using the ELISA method in diabetic pregnant women in compared with non -diabetic pregnant women in Sanandaj, Kurdistan, west of Iran

Background: Toxoplasma gondii is an opportunistic parasitic protozoan, which is a causative agent of serious complications such as abortion or fetal still birth in pregnant women. The purpose of this study was evaluating the seroprevalence of toxoplasmosis and risk factors in diabetic pregnant women (case) in comparison with non-diabetic pregnant women (control) from Sanandaj, Kurdistan, west of Iran. Methods: : In this case-control study Toxoplasma gondii antibodies were tested in 91 cases as well as 90 controls from referred the Toohid hospital diabetes center using ELISA (enzyme-linked immunosorbent assay) method during June 2018 to October 2019 in Sanandaj, Kurdistan, west of Iran. The collected data were analyzed by SPSS 19 and using Chi-Square and Fisher tests. Results: : The seropositivity for anti-Toxoplasma IgG in case group was 33% and 15.6% in the control group ( p = 0.006) showing a statistically significant difference between groups, while for anti-Toxoplasma IgM ( p = 0.31) showing no statistically significant differences between two groups. A significant relationship was observed between age ( p = 0.024) and abortion history ( p = 0.05) with anti-Toxoplasma IgG antibodies in cases and controls. Conclusion: The results of current study indicated statistically significant relationship between diabetes and toxoplasmosis. The abortion history and increase of age was found to be a major T. gondii infection risk factor.