Effects of BenShiHuPoSan on Th1/Th2 Drift in Endometriosis Model Rats

Objective:By comparing the changes of IFN-γ andIL-4 in endometriosis model rats in before and after using BenShiHu-PoSan(BSHPS),we discuss about the Effects of BSHPS on Th1/Th2 drift in Endometriosis.Methods:First,establish the rat model of EMs by transplanting autologous endometrium to the abdominal wall.Then divide the rats randomly into 5 groups:normal group,pseudo operation group,disease group,BSHPS group and danazol group.Finally,detect the levels of IFN-γ and IL-4 by ELISA,after dosing for 4 weeks.Results:Compared with the disease group,the ratio of IFN-Y/IL-4 in BSHPS group is significantly reduced(P0.05).Conclusion:Th2 cells drift to Th1 cells in EMs model rats,that has a stimulative effect on the growth of ectopic endometrium.BSHPS can correct the Th1/Th2 drift,and has a certainly therapeutic effect on EMs.