Short-Term Outcomes of Anterior Bilateral Sacrospinous Fixation Using the Splentis® Tissue Anchoring System for Pelvic Organ Prolapse: A Retrospective Cohort Study

Short-Term Outcomes of Anterior Bilateral Sacrospinous Fixation Using the Splentis® Tissue Anchoring System for Pelvic Organ Prolapse: A Retrospective Cohort Study | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 5 November 2025 V1 Latest version Share on Short-Term Outcomes of Anterior Bilateral Sacrospinous Fixation Using the Splentis® Tissue Anchoring System for Pelvic Organ Prolapse: A Retrospective Cohort Study Authors : Gert Naumann [email protected] , Zaklina Savic-Mitic , and Carolin Gramm Authors Info & Affiliations https://doi.org/10.22541/au.176232078.89221153/v1 246 views 161 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Objective: To assess short-term outcomes of Anterior Bilateral Sacrospinous Fixation (ABSSLF) with Splentis for apical pelvic organ prolapse (POP). Design: Retrospective, single-arm cohort. Setting: German tertiary referral urogynaecology hospital. Population: 334 women with apical POP-Q ≥2 treated between 2016-2023. Methods: Patient records review for collecting perioperative data, NPRS-11 pain, Pelvic Floor Questionnaire. Pre-post differences were analysed with Wilcoxon tests; effect sizes reported as robust Cohen’s d with bootstrapped 95% CIs. Main Outcome Measures: Combined anatomical and surgical success (apical POP-Q 0–1 and no reoperation), patient satisfaction, pelvic-floor function, and adverse events. Results: Follow-up was 11.3 weeks (IQR 8.86-13.82). Success rate was 98.80% (n=330/334). Apical POP-Q improved from median 3 to 0 (d=5.45, 95%CI 5.13–5.92; p<0.0001), with concomitant improvements in anterior and posterior compartments. Pelvic floor function improved 7.70 points (d=1.91, 95%CI 1.47–2.33; p<0.0001), with prolapse symptoms reduction (d=2.70, 95%CI 1.97–3.84), improved bladder (d=0.84, 95%CI 0.66–1.06), bowel (d=0.44, 95%CI 0.25–0.67), and sexual function (d=0.39, 95%CI 0.15–0.54). Patient satisfaction was 97.90% (n=327/334). Median surgery duration was 19 minutes (IQR 16–24). Adverse events included: 0.30% intraoperative blood loss >200 mL (n=1/334), 0.90% partial removals due to mesh exposure (n=2/334) and infection (n=1/334); 1.20% residual urine >100 mL (n=4/334), 0.60% moderate pain (n=2/334), and 7.19% mild pain (n=24/344). Conclusions: Splentis showed high short-term anatomical success and functional improvement with low morbidity, supporting it as a uterus-preserving option for apical POP. Long-term studies are needed to confirm durability. Funding: HELIOS Klinikum Erfurt (sponsor); Promedon GmbH (financial support). Supplementary Material File (naumann_manuscript_v1.docx) Download 685.67 KB Information & Authors Information Version history V1 Version 1 05 November 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords gynaecological surgery gynaecological surgery: prolapse minimal access surgery urogynaecology: surgical treatment Authors Affiliations Gert Naumann [email protected] HELIOS Klinikum Erfurt View all articles by this author Zaklina Savic-Mitic HELIOS Klinikum Erfurt View all articles by this author Carolin Gramm HELIOS Klinikum Erfurt View all articles by this author Metrics & Citations Metrics Article Usage 246 views 161 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Gert Naumann, Zaklina Savic-Mitic, Carolin Gramm. Short-Term Outcomes of Anterior Bilateral Sacrospinous Fixation Using the Splentis® Tissue Anchoring System for Pelvic Organ Prolapse: A Retrospective Cohort Study. Authorea . 05 November 2025. DOI: https://doi.org/10.22541/au.176232078.89221153/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. 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