Ovarian reserve in infertile women with chronic pelvic inflammatory disease

Objective: To assess ovarian reserve among infertile women with chronic pelvicinflammatory disease (PID).Materials and Methods: A prospective study comprised of 35 women (study group A) withclinically and laparoscopically diagnosed PID and 15 cases as control. All cases were assayed for day 3 serum FSH, E2 and inhibin B.Results: In group A, day 3 FSH & E2 were significantly higher than control (11.2±6 mIU/m1and 68.5±21 pg/ml versus 5.3±3 mIU/ml and 41.2±16 pg/ml, P < 0.05). While serum inhibin B was significantly reduced in group A (40±19 pg/ml) compared to the control (60±10pg/ml). Serum inhibin B was negatively correlated with serum FSH in patients with PID.Conclusion: Ovarian reserve appears to be relatively diminished in women with PID. Thisobservation denotes progressive loss of ovarian reserve in cases of PID due to poor follicular development.