Adenomyosis – An Overview
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Abstract
Adenomyosis is a benign uterine disorder in which there is a pathological presence of endometrial glands and stroma in the myometrium. Symptoms can include abnormal uterine bleeding, dysmenorrhea, dyspareunia, or infertility; one-third of women, however, remain asymptomatic.[1] [2] Since many of these symptoms also occur in other gynecological diseases such as endometriosis and uterine fibroids, which often co-exist with adenomyosis, making a clinical diagnosis can be difficult. In the past, adenomyosis was only diagnosed on histopathology after a hysterectomy. With the combination of a patient's risk factor profile, clinical symptoms, and imaging diagnostic tools such as transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI), clinicians are able to identify adenomyosis in a non-invasive way.[1] [3] [4] [5] The diagnosis of adenomyosis has been increasing in young women of reproductive age and conservative treatment is essential in those who prefer to maintain fertility.[1] [5] Since adenomyosis greatly impacts quality of life, it is important for clinicians to properly diagnose and treat these women to optimize clinical outcome.
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Cited by (3)
- Inhibition of Sonic Hedgehog signaling pathway by GANT61 alleviates adenomyosis by suppressing epithelial-to-mesenchymal transition, cell migration and proliferation 2026
- Transcriptomic-based analysis of endometrial tissues from adenomyosis patients reveals significant inflammation biomarkers: A bioinformatics study 2025
- Menorrhagia and the Menopausal Transition 2024
Source provenance
- europepmc
- last seen: 2026-06-13T17:20:28.795615+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:23:57.700195+00:00
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