IMPACTO DA ENDOMETRIOSE NA INFERTILIDADE: UMA REVISÃO SISTEMÁTICA DOS MECANISMOS PATOFISIOLÓGICOS E ABORDAGENS TERAPÊUTICAS
This integrative review analyzes the pathophysiological mechanisms linking endometriosis to infertility, highlighting how pelvic adhesions and immunological changes contribute to reproductive impairment in women of reproductive age.
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This integrative review examines the pathophysiological mechanisms and therapeutic approaches linking endometriosis to infertility in women of reproductive age. The authors analyzed studies from 2004 to 2024 to evaluate etiopathogenic theories such as retrograde menstruation and their impact on pelvic adhesions and immune alterations that impair fertility. Key findings highlight that early diagnosis through imaging and biomarkers is critical, alongside personalized management strategies that address both clinical symptoms and psychological burdens. This paper is centrally about endometriosis — specifically its role as a significant cause of infertility and the need for multidisciplinary treatment approaches.
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