Endometriosis and Gynecological Cancer

Mihai Emil Căpîlna, B Szabó, Lucian Pușcașiu, Aron Toma, Cosmin Rugină
In: Current Women's Health Reviews · 2012 · vol. 8(2) , pp. 150–157 · doi:10.2174/157340412800194867 · W2316171128
article OA: closed CC0
Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This systematic review examines the links between endometriosis and gynecological cancer, finding evidence that ovarian tumors can arise from endometriosis and discussing risk factors, genetics, and pathways involved.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Abstract

Objective: Endometriosis has been suspected of playing a role in the etiology of ovarian cancer. Design: This systematic review addresses the parallels and specific relationship of endometriosis and gynecological cancer regarding risk factors, histological data, genetic alterations, aberrant activation of oncogenic and antiapoptotic pathways, and options in clinical diagnosis. Data sources and eligibility criteria: We have performed a Pubmed search looking for all articles in English, using as key words "endometriosis", "ovarian cancer", "gynecologic cancer", "pathogenesis". Results: The evidence of the published studies suggests that ovarian tumors can arise from more than one potential source, endometriosis being one of these sources. Conclusion: Understanding the mechanism of the development of endometriosis and elucidating its pathogenesis and pathophysiology are intrinsic to the prevention of endometriosis associated ovarian cancer and the search for effective therapies. Keywords: Endometriosis, epidemiology, molecular pathogenesis, ovarian cancer
Full text 980 characters · extracted from oa-doi-fallback · 4 sections · click to expand

Abstract

Design: This systematic review addresses the parallels and specific relationship of endometriosis and gynecological cancer regarding risk factors, histological data, genetic alterations, aberrant activation of oncogenic and antiapoptotic pathways, and options in clinical diagnosis. Data sources and eligibility criteria: We have performed a Pubmed search looking for all articles in English, using as key words “endometriosis”, “ovarian cancer”, “gynecologic cancer”, “pathogenesis”.

Results

The evidence of the published studies suggests that ovarian tumors can arise from more than one potential source, endometriosis being one of these sources.

Conclusion

Understanding the mechanism of the development of endometriosis and elucidating its pathogenesis and pathophysiology are intrinsic to the prevention of endometriosis associated ovarian cancer and the search for effective therapies.

Keywords

Endometriosis, epidemiology, molecular pathogenesis, ovarian cancer

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
unpaywall
last seen: 2026-08-03T06:41:53.707437+00:00
License: CC0 · commercial use OK