Management of Gynecologic and Urologic Aspects of Sjögren’s

Rita Melkonian
In: The Sjögren's Book · 2022 · pp. 338–352 · doi:10.1093/oso/9780197502112.003.0035 · W4280631181
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This chapter reviews gynecologic and urologic complications of Sjögren's, including vaginal dryness, UTIs, pregnancy risks, lichen sclerosus, and premature ovarian failure.

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Abstract

Abstract Sjögren’s patients are at increased risk for a variety of unique gynecologic and urologic complications, and this chapter will discuss a range of these complications. Vaginal dryness and dyspareunia are the most common manifestations of Sjögren’s and can often be successfully treated with topical products. Frequent urinary tract infections can occur. Pregnancy poses its own unique problems, with the potential for fetal heart block or miscarriage connected with antiphospholipid antibodies; a multidisciplinary approach with the rheumatologist, gynecologist, and pediatrician is key to the successful treatment and management of patients with Sjögren’s. The rare manifestation of lichen sclerosus needs to be addressed by the patient’s gynecologist, as this condition can cause severe vulvovaginal atrophy and regression. The pathogenesis of gynecologic manifestations such as premature ovarian failure, endometriosis, amyloidosis, and interstitial cystitis in Sjögren’s patients needs further research.

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Condition tags

endometriosisdyspareuniainterstitial_cystitis

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