Endometriosis and infertility: the role of exogenous lipid peroxides in the peritoneal fluid
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This study found that lipid peroxide levels in the pelvic peritoneal fluid were not elevated in patients with endometriosis compared to controls, suggesting accelerated lipid peroxidation does not contribute to endometriosis-associated infertility.
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Abstract
OBJECTIVE: To determine if lipid peroxides were raised in the pelvic peritoneal fluid of patients with endometriosis.
DESIGN: Control study involving patients with and without endometriosis.
METHODS: The lipid peroxide (malondialdehyde) levels in the pelvic PF of 12 patients with moderate-to severe endometriosis, 15 patients with minimal-mild endometriosis and 13 patients with normal pelvises were compared.
RESULTS: The level of lipid peroxides were not affected by the presence nor the severity of endometriosis.
CONCLUSION: Accelerated lipid peroxidation does not appear to play a role in the causal relationship between endometriosis and infertility.
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- europepmc
- last seen: 2026-09-01T06:12:48.306406+00:00
- pubmed
- last seen: 2026-05-13T22:11:18.900538+00:00
- unpaywall
- last seen: 2026-09-01T06:29:04.589233+00:00
License: public-domain-us
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine