Sleep Quality, Cancer-Related Fatigue, and Health-Related Quality of Life Among Omanis Hospitalized Patients with Cancer: A Cross-Sectional Study.

Abstract Purpose: This study aimed to examine the difference in HRQoL by participants’ characteristics and to investigate the determinants of health-related quality of life HRQoL among Omani hospitalized patients with cancer.Methods: This cross-sectional study was conducted in two oncology centers in Oman. Omani hospitalized patients with breast, thyroid, colorectal, stomach, and prostate cancer were recruited using convenience sampling. Participants completed Arabic versions of self-reported questionnaires: Pittsburgh Sleep Quality Index, Brief Fatigue Inventory scales and Functional Assessment of Cancer Therapy. Descriptive and inferential statistics were performed. T-test, ANOVA and multiple linear regression analysis was utilized to determine predictors of HRQOL.Results: in total, 275 participants were recruited (Meanage= 52 years). About 64 % of the participates reported poor sleep and 18.5% reported severe cancer-related fatigue. Sleep quality, cancer-related fatigue, age, and prostate and thyroid cancer were significant predictors of HRQoL (F (5, 269) = 26.26, p < 0.000) and they explained 33% of the variances in the HRQoL (R2 = .328).Conclusions: This study highlights the impact of sleep quality and caner-related fatigue on the HRQOL among Omanis hospitalized with cancer. Thus, sleep quality and cancer-related fatigue should be assessed routinely during hospitalization of oncology patients with special attention patients’ age.