miR-31 and miR-145 as Potential Non-Invasive Regulatory\nBiomarkers in Patients with Endometriosis

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This study investigated miR-31 and miR-145 as potential non-invasive regulatory biomarkers in patients diagnosed with endometriosis.

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This study evaluated whether circulating microRNAs miR-31 and miR-145 could serve as non-invasive regulatory biomarkers in patients with endometriosis, using a case–control design and measuring microRNA levels in patient samples. The authors reported differences in the expression of these microRNAs between endometriosis patients and comparison subjects, supporting their potential as biomarker candidates. The paper’s main caveat is that biomarker evaluation was based on the measured circulating levels in the sampled population without broader external validation or additional mechanistic confirmation. This paper is centrally about endometriosis — it focuses specifically on miR-31 and miR-145 as non-invasive regulatory biomarkers in endometriosis.

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Cell Journal (Apr 2018) miR-31 and miR-145 as Potential Non-Invasive Regulatory Biomarkers in Patients with Endometriosis - Oranous Bashti, - Mehrdad Noruzinia, - Masoud Garshasbi, - Morteza Abtahi Affiliations - Oranous Bashti - Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran - Mehrdad Noruzinia - Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran - Masoud Garshasbi - Department of Medical Genetics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran - Morteza Abtahi - Dena Hospital, Shiraz, Iran - DOI - https://doi.org/10.22074/cellj.2018.5850 - Journal volume & issue - Vol. 20, no. 2 pp. 293 – 293 WeChat QR code

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endometriosis

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