[A previously unpublished indication for sulpiride: functional uterine hemorrhages].

In: Journal de gynecologie, obstetrique et biologie de la reproduction · 1977 · vol. 6(8) , pp. 1133–8 · PMID:608930 · W2431048222
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Abstract

Sulpiridin has been shown to be remarkably efficient in treating functional uterine haemorrhage (70 per cent success). It is especially so in the pre-menopause. Its mode of action takes place on three levels: the hypothalamus, where it works on the clonic centre for the release of gonadotrophins (the tonic centre not being affected); the ovaries, where it lessens the sensitivity of the reaction of the ovary to gonadotrophins; the uterus, where there is direct action on the thickness of the mucous lining of the uterus and on its blood supply.

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