Primary adenocarcinoma arising from endometriosis of the rectovaginal septum: a case report

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This case report details a primary adenocarcinoma that developed from endometriosis located in the rectovaginal septum.

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Abstract

Adenocarcinomas developing in endometriotic lesions have been reported, most commonly in the ovary. The rectovaginal septum is a rare location of this neoplastic transformation. We report a case of primary adenocarcinoma arising from endometriosis of the rectovaginal septum in a 25-year-old woman presenting with lower abdominal pain and dyspareunia. Diagnostic and treatment modalities were discussed. Immunohistochemical studies of different keratin subtypes and CA125 expression of the tumor cells are of interest for the diagnosis. Preoperative radiation therapy promotes clinical symptoms relief, tumor volume reduction, and better radical surgical approach.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Endometriosis Rectal Neoplasms Vaginal Neoplasms Adenocarcinoma Adenocarcinoma Adult Antineoplastic Combined Chemotherapy Protocols Antineoplastic Combined Chemotherapy Protocols Cisplatin Cisplatin Colectomy Endometriosis Female Gynecologic Surgical Procedures Humans Neoadjuvant Therapy Paclitaxel Paclitaxel Radiotherapy

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (10)

Cited by (10)

Source provenance

europepmc
last seen: 2026-08-29T06:12:09.280863+00:00
openalex
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pubmed
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License: CC0 · commercial use OK