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LUNG CANCER LOCATION PATTERNS: Why tumors prefer their sites | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 15 January 2025 V1 Latest version Share on LUNG CANCER LOCATION PATTERNS: Why tumors prefer their sites Authors : Gabriel Gomes Vieira Ribeiro Leite 0000-0003-0731-9770 [email protected] and Ana Maria Magalhães Valle Cundari Authors Info & Affiliations https://doi.org/10.22541/au.173697559.90154023/v1 205 views 111 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Lung cancer is worldwide the leading non-skin cancer-related cause of death and the second most diagnosed malignancy. Currently, many immunohistochemistry essays can provide precise end of line histological diagnosis, improving overall survival through efficient individualized treatment schemes. There seems to be a radiological correlation between the two basic histological tumor subtypes (adenocarcinoma and squamous cells carcinoma) and nodule site presentation in chest imaging, and although this is considered in many radiology manuals, the reasons for such presentation patterns are seldom investigated. We intend to present hypothesis and reasonable explanations for the practical consensus widely acknowledged in the manuals, considering cell types in the lung topography and histological markers in carcinogenesis which should be able to clarify wether the imaging pattern is statistically true and why certain tumor types prefer their usual sites, being adenocarcinomas preferably peripheral and squamous cell carcinoma central. Supplementary Material File (lung cancer location - article v.6 (1).pdf) Download 247.05 KB Information & Authors Information Version history V1 Version 1 15 January 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords chest x-rays lung adenocarcinoma lung cancer pattern analysis squamous cell carcinoma Authors Affiliations Gabriel Gomes Vieira Ribeiro Leite 0000-0003-0731-9770 [email protected] Department of Microbiology, University of Itaúna View all articles by this author Ana Maria Magalhães Valle Cundari Professor of Radiology, University of Itaúna View all articles by this author Metrics & Citations Metrics Article Usage 205 views 111 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Gabriel Gomes Vieira Ribeiro Leite, Ana Maria Magalhães Valle Cundari. LUNG CANCER LOCATION PATTERNS: Why tumors prefer their sites. Authorea . 15 January 2025. DOI: https://doi.org/10.22541/au.173697559.90154023/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. 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