Expression and significance of antibody to transferrin in patients with endometriosis

An ELISA method was established by using transferrin as coating antigen to detect the serum samples from 38 female with endometriosis (20 cases with stage I-II, 9 cases with stage III, 9 cases with stage IV), 30 benign lesions, 40 normal female control. The positive rates of antibody transferrin to in the serum of patients with endometriosis (specificity 98.9%, sensitivity 94.7% and accuracy 97.6%) were significantly higher than those in control group (P<0.01). There were no defferences among stages of endometriosis. Detecting antibody transferrin to may will provide specific noninvasive diagnosis for endometriosis.