Split-QF system for fine-tuned transgene expression in Drosophila

preprint OA: closed CC-BY-NC-ND-4.0
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Abstract

The Q-system is a binary expression system that works well across species. Here we report the development of a split-QF system that drives strong expression, is repressible by QS and inducible by quinic acid. The split-QF system is fully compatible with existing split-GAL4 and split-LexA lines for advanced intersectional experiments, thus greatly expanding the range of possible anatomical, physiological and behavioural assays in Drosophila.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00
unpaywall
last seen: 2026-05-23T02:00:01.238055+00:00
License: CC-BY-NC-ND-4.0