Indications and Histopathological Analysis of Hysterectomy Specimens

Shabana Bano Soomro, Hina Pirzada, Ahmal Fawad Zafar, Mutayyaba Majeed, Sadia Habib, Sania
In: Pakistan Journal of Medical and Health Sciences · 2022 · vol. 16(7) , pp. 319–320 · doi:10.53350/pjmhs22167319 · W4292237640
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This study prospectively analyzed hysterectomy specimens from 50 women, finding abnormal uterine bleeding and abdominal masses to be primary indications, with leiomyoma and adenomyosis being the most frequent histopathological findings.

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This prospective study evaluated the clinical indications and histopathological findings in fifty women undergoing hysterectomy at a hospital in Larkana between 2021. The majority of participants presented with abnormal uterine bleeding or abdominal masses, leading to surgical intervention for conditions such as uterine prolapse and fibroids. Histopathological examination revealed that leiomyoma was the most frequent diagnosis, accounting for twenty-nine percent of cases, while adenomyosis was also identified among the specimens. Relevance to endometriosis: listed as one indication for GnRH antagonists, though the paper's main focus is uterine fibroids.

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Abstract

Objective: To examine the indications and histopathological analysis of hysterectomy specimens. Study Design: Prospective study. Place and Duration of Study: Department of Obstetrics & Gynaecology, Shaikh Zayed Women Hospital Larkana from 1st January 2021 to 31st December 2021. Methodology: Fifty women undergoing hysterectomies with an age greater than 18 years were enrolled as study participants. Partial or complete hysterectomy was performed in each patient and the samples gained post hysterectomy were placed in 10 percent formalin until histopathological examination was performed. The process of hysterectomy was done by a qualified surgeon keeping quality surgical standards. Demographic details including age, gender as well as other information regarding clinical symptoms, diagnosis and clinical history were documented on a well-structured questionnaire. Results: The mean age was 34.4±5.4 years with most of the women within the age group of 40-49 years and 68% of the women with abundant menstrual bleed followed by presentation of abdominal mass. In most of the females a uterus fibroid was presented whereas UV prolapse was also common in women indicating towards hysterectomy. Leiomyoma was presented highest on histopathological report findings such as in 29% of the cases followed with adenomyosis reporting. Conclusion: Every hysterectomy sample should be evaluated properly and timely for post-operative management and for the exact diagnosis of underlying disease. Keywords: Hysterectomy; Evacuation; Pathology; Malignancies
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Objective

To examine the indications and histopathological analysis of hysterectomy specimens. Study Design: Prospective study. Place and Duration of Study: Department of Obstetrics & Gynaecology, Shaikh Zayed Women Hospital Larkana from 1st January 2021 to 31st December 2021. Methodology: Fifty women undergoing hysterectomies with an age greater than 18 years were enrolled as study participants. Partial or complete hysterectomy was performed in each patient and the samples gained post hysterectomy were placed in 10 percent formalin until histopathological examination was performed. The process of hysterectomy was done by a qualified surgeon keeping quality surgical standards. Demographic details including age, gender as well as other information regarding clinical symptoms, diagnosis and clinical history were documented on a well-structured questionnaire.

Results

The mean age was 34.4±5.4 years with most of the women within the age group of 40-49 years and 68% of the women with abundant menstrual bleed followed by presentation of abdominal mass. In most of the females a uterus fibroid was presented whereas UV prolapse was also common in women indicating towards hysterectomy. Leiomyoma was presented highest on histopathological report findings such as in 29% of the cases followed with adenomyosis reporting.

Conclusion

Every hysterectomy sample should be evaluated properly and timely for post-operative management and for the exact diagnosis of underlying disease.

Keywords

Hysterectomy; Evacuation; Pathology; Malignancies

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adenomyosis

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