All TGF-β ligands are expressed in peritoneal fluid from women with and without endometriosis.

Vicky J. Young (627900), Jeremy K. Brown (101879), Philippa T. K. Saunders (34887), W. Colin Duncan (209189), Andrew W. Horne (209218)
2015 · doi:10.1371/journal.pone.0106773.g001 · W6960807982
other OA: green CC0
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Abstract

TGF-β1 was significantly increased in peritoneal fluid from women with endometriosis compared to women without. Levels of TGF-β2 do not change between women with and without endometriosis. TGF-β3 levels appear to increase in women with endometriosis however this is not a significant change. Cultured HPMCs secreted TGF-β1 protein in-vitro. n = 12 peritoneal fluid, n = 3 HMPC (*p<0.05).
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The Peritoneum Is Both a Source and Target of TGF-β in Women with Endometriosis Figure 1 All TGF-β ligands are expressed in peritoneal fluid from women with and without endometriosis. TGF-β1 was significantly increased in peritoneal fluid from women with endometriosis compared to women without. Levels of TGF-β2 do not change between women with and without endometriosis. TGF-β3 levels appear to increase in women with endometriosis however this is not a significant change. Cultured HPMCs secreted TGF-β1 protein in-vitro. n = 12 peritoneal fluid, n = 3 HMPC (*p<0.05).

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