Risk estimates for microcephaly related to Zika virus infection - from French Polynesia to Bahia, Brazil

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Abstract

Zika virus (ZIKV) infection during pregnancy has been linked to birth defects, 1 yet the magnitude of risk remains uncertain. A study of the Zika outbreak in French Polynesia estimated that the risk of microcephaly due to ZIKV infection in the first trimester of pregnancy was 0.95% (95% confidence interval: 0.34-1.91%), based on eight microcephaly cases identified retrospectively in a population of approximately 270,000 people with an estimated 66% ZIKV infection rate. 2

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