A case of large bladder endometriosis treated with TUR-BT and hormonal therapy

Michiko Kodama, Kosuke Hiramatsu, Yonghwi Kim, Kentaro Okuno, Yoshiko Komoto, Hiroaki Hushimi, Masahiko Takemura
In: JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY · 2009 · vol. 25(2) , pp. 395–398 · doi:10.5180/jsgoe.25.395 · W2317712629
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This case describes successful treatment of large bladder endometriosis with transurethral resection and hormonal therapy, which reduced lesion size and alleviated symptoms for 14 months.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-08 ⓘ

This paper reports a case of a 40-year-old woman with severe bladder endometriosis involving the bladder trigone and the left urethral orifice, presenting with dysmenorrhea and lower urinary tract symptoms. Diagnosis and assessment of lesion extent were confirmed using MRI and transurethral resection of tumor (TUR-BT), but complete surgical resection was not performed due to anticipated difficulty and concern about impairment of bladder function. Treatment with leuprolide acetate followed by genogest reduced the tumor size and alleviated symptoms for 14 months, with the paper noting that partial cystectomy may be essential for complete remission and that recurrence has been reported, especially for lesions involving the bladder fundus. This paper is centrally about endometriosis—specifically large bladder endometriosis treated with TUR-BT and hormonal therapy.

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Abstract

A 40-year-old woman suffered from severe bladder endometriosis involving the bladder trigone and left urethral orifice. Severe dysmenorrhea, lower urinary tract symptoms (pollakiurea and discomfort while urinating) were the chief complaints. The findings of magnetic resonance imaging (MRI) and transurethral resection of the tumor (TUR-BT) confirmed the diagnosis and revealed the extent of the lesion. Surgical resection of the lesion was not performed because of the difficulty anticipated for complete resection and the fear of affecting the bladder function after the resection. The administration of leuprolide acetate followed by genogest successfully reduced the tumor size and alleviated the symptoms for 14 months. Partial cystectomy is essential for complete remission and is indicated for patients who desire pregnancy. However, a high incidence of recurrence after resection of the tumor that involved the bladder fundus has been reported. Hence, it is important to individualize the treatment strategy for bladder endometriosis by accurately evaluating the location and the extent of the lesion.

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Condition tags

endometriosisbladder_endometriosisdysmenorrhea

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References (8)

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last seen: 2026-06-10T17:14:06.276822+00:00
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