Efeitos da suplementação de vitamina D em pacientes com endometriose

Luanna de Souza Côrtes Cremonez, Luisa Leite Moreira, Giovani de Paula Migotto, Giullia de Araújo Zamboni, Oswaldo Aparecido Caetano
In: Cuadernos de Educación y Desarrollo · 2024 · vol. 16(2 Edição Especial) · doi:10.55905/cuadv16n2-ed.esp.341 · W4390910714
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-07 ⓘ

This study investigated the effects of vitamin D supplementation in patients with endometriosis, a condition characterized by endometrial tissue outside the uterus.

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The paper is a narrative discussion focused on endometriosis, describing the condition as ectopic endometrial tissue outside the uterine lining and noting that available treatments are limited. It considers vitamin D supplementation as a nutritional intervention that could play a role in preventing and treating endometriosis and the associated pain, drawing on referenced literature about nutrition and vitamin D. The main limitation is that the text provided does not include original trial or mechanistic data, relying instead on citation of prior reviews and a randomized placebo-controlled trial. This paper is centrally about endometriosis — it focuses on the effects of vitamin D supplementation in patients with endometriosis.

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Abstract

A endometriose é caracterizada pela presença de tecidos endometriais fora do revestimento uterino, geralmente na superfície externa do útero, trompas, ovários, parede abdominal ou no intestino. As opções de tratamento para endometriose são limitadas, portanto, intervenções nutricionais podem ser úteis na prevenção e tratamento da endometriose e na dor associada.
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Efeitos da suplementação de vitamina D em pacientes com endometriose DOI: https://doi.org/10.55905/cuadv16n2-ed.esp.341Palavras-chave: endometriose, saúde reprodutiva, vitamina DResumo A endometriose é caracterizada pela presença de tecidos endometriais fora do revestimento uterino, geralmente na superfície externa do útero, trompas, ovários, parede abdominal ou no intestino. As opções de tratamento para endometriose são limitadas, portanto, intervenções nutricionais podem ser úteis na prevenção e tratamento da endometriose e na dor associada. Referências BARNARD, N. D. et al. Nutrition in the prevention and treatment of endometriosis: A review. Frontiers in Nutrition, v. 10, 2023. DOI: https://doi.org/10.3389/fnut.2023.1089891 KALAITZOPOULOS, D. R. et al. Effects of vitamin D supplementation in endometriosis: a systematic review. Reproductive biology and endocrinology: RB&E, v. 20, n. 1, p. 176, 2022. DOI: https://doi.org/10.1186/s12958-022-01051-9 NODLER, J. L. et al. Supplementation with vitamin D or ω-3 fatty acids in adolescent girls and young women with endometriosis (SAGE): a double-blind, randomized, placebo-controlled trial. The American Journal of Clinical Nutrition, v. 112, n. 1, p. 229–236, 2020. DOI: https://doi.org/10.1093/ajcn/nqaa096

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