481 Dienogest For the Treatment of Dyspareunia Caused by Endometriosis

Dyspareunia - painful sexual intercourse is one of the common sexual dysfunction among women and it can be caused not only by psychogenic but organic diseases too, including endometriosis that affects 10%-15% of reproductive aged women. Possibility of treatment dyspareunia among women suffered with endometriosis is valuable for Improvement of female's quality of life. The aim of our study was to evaluate the efficacy of dienogest for the treatment of dyspareunia caused by endometriosis. 34 women aged 18-39 years (the average age in study group was 32±4.1) with endometriosis (confirmed by clinical and/or ultrasound and/or laparoscopy) suffered from dyspareunia were included in the prospective open-label clinical study. Criteria for exclusion were other treatment before 6 month and existence of pelvic inflammatory disease. Patients received 2 mg dienogest for 6 month. Pain score during sexual intercourses were evaluated by using 100 mm visual analog scale(VAS) before and after 3 and 6 month of treatment.