[Selective progesterone receptor modulators: future clinical applications]
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Selective progesterone receptor modulators (SPRMs) are valuable in women's health, primarily by impacting the endometrium to reduce uterine fibroid volume and bleeding, and are being explored for endometriosis and contraception.
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Abstract
Progesterone antagonists belong to the family of selective progesterone receptor modulators. SPRMs already have several applications in women's health. Their main value lies in their effect on endometrium. For example, they can be used to reduce tumor volume and uterine bleeding before uterine myoma surgery. They are also being evaluated for the treatment of endometriosis, and for estrogen-free contraception.
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Source provenance
- europepmc
- last seen: 2026-06-13T06:22:48.782012+00:00
- pubmed
- last seen: 2026-05-13T22:14:11.755070+00:00
- unpaywall
- last seen: 2026-06-14T06:15:46.576397+00:00
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Courtesy of the U.S. National Library of Medicine
Courtesy of the U.S. National Library of Medicine