Subdermal Insertable Sensors: Characteristics and Applications

Subdermal Insertable Sensors: Characteristics and Applications | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 21 November 2025 V1 Latest version Share on Subdermal Insertable Sensors: Characteristics and Applications Authors : Haoyuan Zhu , Lin Du , Xilin Liu , and Andrew G. Richardson 0000-0002-4752-3867 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.176376449.93603809/v1 355 views 175 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Continuous monitoring of chronic diseases with mobile health tools is rapidly advancing to improve patient care. Wearable sensors placed on or near the skin remain the dominant paradigm for collecting physiological data noninvasively during activities of daily living. However, wearable sensors have their limitations. Epidermal sensors are fundamentally limited by the information barrier that the skin presents. Furthermore, environmental factors impact stability and longevity of wearables. An alternative technology is the expanding class of minimallyinvasive subdermal sensors, also called insertables. Characteristics of insertable sensors are reviewed, emphasizing state-of-theart approaches for achieving biocompatibility, remote powering, and wireless data transmission from their location under the skin. Next, key applications for subdermal sensors are analyzed, including three current clinical devices: insertable cardiac monitors, insertable continuous glucose monitors, and sub-scalp epilepsy monitors. Finally, future directions for material and system innovations, addressing challenges such as fibrotic encapsulation and energy efficiency, are explored to suggest potential next-generation subdermal biosensors that address unmet needs in chronic disease monitoring. Supplementary Material File (zhu_subdermal_insertables_v1.pdf) Download 5.01 MB Information & Authors Information Version history V1 Version 1 21 November 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords biosensors implantables remote patient monitoring wearables wireless power transfer Authors Affiliations Haoyuan Zhu View all articles by this author Lin Du View all articles by this author Xilin Liu View all articles by this author Andrew G. Richardson 0000-0002-4752-3867 [email protected] View all articles by this author Funding Information National Science Foundation CBET-2505739 Andrew G. Richardson Metrics & Citations Metrics Article Usage 355 views 175 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Haoyuan Zhu, Lin Du, Xilin Liu, et al. Subdermal Insertable Sensors: Characteristics and Applications. Authorea . 21 November 2025. 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