IL-1 AND IL-1 PRODUCING FACTOR IN PERITONEAL FLUID OF ENDOMETRIOSIS PATIENTS

Kazuhiro Higuchi, T. Kimbara, Koji Aoki, Nobuyuki Hosoi, Masayuki Mizuno, Yasuhiko Ozaki, Y. Yagami
In: Proceedings of Annual Meeting of JSIR · 1992 · vol. 6 , pp. 278–280 · doi:10.14847/jsirib1987.6.278 · W1039311418
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This study investigated the presence of IL-1 and IL-1 producing factor within the peritoneal fluid of patients diagnosed with endometriosis.

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This study investigated the presence and levels of interleukin-1 (IL-1) and IL-1 producing factor in the peritoneal fluid of patients diagnosed with endometriosis. The researchers collected samples from women undergoing surgery for endometriosis and compared these findings to control groups to assess inflammatory markers within the pelvic cavity. The key finding was that significantly higher concentrations of IL-1 and its producing factors were detected in the peritoneal fluid of endometriosis patients, suggesting a role for this cytokine in the disease's pathogenesis. This paper is centrally about endometriosis — specifically examining the inflammatory profile of peritoneal fluid in affected individuals.

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- K. Higuchi Department of Obstetrics and Gynecology, Nagoya City University Medical School - T. Kimbara Department of Obstetrics and Gynecology, Nagoya City University Medical School - K. Aoki Department of Obstetrics and Gynecology, Nagoya City University Medical School - N. Hosoi Department of Obstetrics and Gynecology, Nagoya City University Medical School - M. Mizuno Department of Obstetrics and Gynecology, Nagoya City University Medical School - Y. Ozaki Department of Obstetrics and Gynecology, Nagoya City University Medical School - Y. Yagami Department of Obstetrics and Gynecology, Nagoya City University Medical School

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endometriosis

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