Endometriosis Pathology Outline

Baidaa Abdulkareem Alwan
In: International Journal of Research in Medical Sciences & Technology · 2021 · vol. 11(1) · doi:10.37648/ijrmst.v11i01.003 · W3173156757
article OA: bronze CC0
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⚙ AI-generated summary by claude@2026-06, 2026-06-12 ⓘ

Endometriosis, characterized by endometrial tissue outside the uterus, causes pain and infertility through inflammation, perinervous infiltration, follicular dysfunction, and peritoneal fluid abnormalities, despite its unclear pathological mechanisms.

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Abstract

Endometriosis is the presence of tissue estrogen-dependent endometrial outside the uterine cavity. The two main symptoms are pain and infertility. It is a common disease, but the whole pathological mechanisms remain poorly understood. However, in addition to the two main pathological theories (implantation and metaplasia), new data have been added: inflammation and perinervous infiltration appear to be two major elements in the mechanism of pain. The basis of infertile process is not dependent on a mechanic cause, but also on disturbances in follicular generation and in fluid abnormality in the peritoneum

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endometriosisinfertility

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